Gene names by organism

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To view genes of a specific organism, please select in the main menu.

Organismsort iconGene nameEtymology
Schizosaccharomyces pombewee1

Yeast gene names consist of just three letters and a number. So, one must be pretty clever to put something descriptive in the name. Like the discoverer of this gene: wee1 mutants divide sooner than they should, so they are wee small.

Schistocerca americanalazarillo

The gene guides growing nerve axons in grasshopper. Lazarillo earns his living by guiding a blind person in a 16. century Spanish novel by an anonymous author "La vida de Lazarillo de Tormes y de sus fortunas y adversidades contadas por el mismo" or  "The Life of Lazarillo of Tormes, his fortunes and misfortunes as told by himself."

Saccharomyces cerevisiaeZZZ1

A yeast gene involved somehow in sleep (???): the mutants respond differently to volatile anesthetics.

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Ovis ariescallipyge

Mutant sheep have huge, muscular bottoms. Callipyge (greek) means "beautiful buttocks".

Luciola lateralisluciferase

Luciferase is a common name for enzymes that catalyze reactions producing light. The name luciferase was coined by the German electrophysiologist Emil Heinrich DuBois-Reymond. Lucifer, the fallen angel, is also known as the light-giver.

Homo sapienship, hop

Hip and hop gene products help other proteins to fold correctly. That is, many proteins require them to acquire the correct 3D structure. For those in doubt, Mc Hawking proves that science and hiphop belong inseparably together. (The primary official names listed by HUGO for these genes are almost equally humorous ST13 and STIP1.)

Homo sapiensJAK-1

Abbreviation for janus kinase. The gene codes an essential kinase (= an enzyme phosphorylating other proteins) that functions in the internal signalling system of cells. In the Janus kinases, there are two phosphate-transferring domains. Thus, it got its name from the Roman two-faced gatekeeper of the heaven Janus. 
The abbreviation JAK is also said to stand for "just another kinase" as there are so overwhelmingly many kinases in the body that no-one can remember them all anyway.

Homo sapiensmad, max

Proteins coded by mad and max bind to each other and take care that genes do not work at the wrong time. Mad Max (Mel Gibson) was on the good side, as well.

Homo sapienspokemon

One of the POK genes (encoding proteins which turn off other genes): POK Erythroid Myeloid Ontogenic factor. Pokemon is an oncogene: if it is mutated, it can cause cancer. In fact, it appears to be a master switch for cancer.
The primary name recommended by OMIM is "ZINC FINGER- AND BTB DOMAIN-CONTAINING PROTEIN 7".

Homo sapienssonic hedgehog

The gene was first found in fruit fly. It was named hedgehog, as the mutant larvae resembled a hedgehog. One of the human hedgehog genes was named sonic hedgehog, according to the Sega computer game character.

Homo sapienstigger

Tigger is a transposable element in the human genome, i.e. it can jump to another location in the genome. Tigger, in A.A. Milne's Winnie the Pooh, was a bouncy, trouncy, flouncy, pouncy character.

Homo sapiensARSE

This is the handy official symbol of the arylsulfatase E gene.

Homo sapiensMT1

This stands for at least eleven different genes in the human.

Homo sapiensTNFRSF1B

This jolly gene (full name: tumor necrosis factor receptor subfamily, member 1B) is also known as TNFR2, TNFBR, TNFR-75 kD, TNFR-80 kD, p75TNFR, p75 and CD120b. In other words, quite normal for a human gene.

Homo sapiensSEMA5A

The full name of this gene is "sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A". When a new gene is found, often all that is known of it is that it resembles some other genes. So, it easily gets named "gene like this and that gene", like this one involved in axonal guidance. Fortunately, this gene is usually called just SEMA5A, which is its official short symbol.

Haemophilus influenzaefucK

The fuculokinase gene of this bacterium is known of this clever abbreviation.

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Escherichia colimazEF

After the Hebrew term 'Ma Ze' ('What is it?'). Later discovered to encode an addiction molecule.

Drosophila melanogastercleopatra

The mutant's interaction with the asp gene is lethal. Queen Cleopatra is said to have committed suicide by a poisonous asp.

Drosophila melanogasterdunce

Dunce flies are impaired in learning. The name also refers to John Duns Scotus, the
founder of Scotist School in the 13th century, who was an opponent to the revival of classical learning.

Drosophila melanogastergustavus

The gene interacts with vasa (Gustavus Vasa was a king of Sweden).

Drosophila melanogastertudor

Mutants don't get any progeny, as happened to the royal Tudor family.

Drosophila melanogastervasa

See gustavus.

Drosophila melanogasteramontillado

Mutant larvae are unable to hatch. In 'The Cask of Amontillado' by Edgar Allan Poe, a man is walled-in while still alive.

Drosophila melanogasterariadne

Without ariadne the growing axons of nerve cells don't find their targets. Ariadne helped the mythological Greek hero Theseus to find his way in Minotaur's labyrinth.

Drosophila melanogasterarleekin

(As well as valiet, tungus, barbos, laska, ikar, rogdi,  pastrel, toi, rafael, milkah, avgust, murashka, beluy, mampus, novichok, mirta, rijiy, diana, zolotistyuy, rosa, gryzun, chyorny, moladietz, dikar, nord, drujok, jack, martik, premjera, visgun, zloday.) These fly mutants have problems in long-term memory. They are named after  Ivan Pavlov's famous drooling dogs.

Drosophila melanogasterlot

As in the Bible: mutants like salt more than usual.

Drosophila melanogastermalvolio

Malvolio gene is needed for normal taste behavior. Malvolio, in Shakespeare's Twelfth Night, 'taste[d] with distempered appetite'.

Drosophila melanogastersarah

Mutant flies are practically sterile. Sarah, Abrahams wife, was infertile for many years, but eventually gave birth to a boy (Gen 21:3).

Drosophila melanogastersmaug

The gene represses activity of the nanos gene (Greek for "dwarf"). In J.R.R. Tolkien's Hobbit, the dragon Smaug drove dwarves away from their caves.

Drosophila melanogasterthor

Thor, God of Thunder, protected Nordic people with his giant hammer, Mjölnir. Nowadays Thor defends fruit flies against diseases, as the gene is involved in their immune defence.

Drosophila melanogastertinman

Tinman mutants lack the heart, as did the Tin Woodman in 'Wizard of Oz'.

Drosophila melanogastervulcan

Vulcan was the Roman God of fire and metal works. Jupiter, his father, threw him from heaven. As he fell down, both of his legs broke. Vulcan mutants have malformed legs.

Drosophila melanogasterbarentsz

In the mutant, mRNA of the oskar gene gets stuck and cannot reach the posterior pole of the egg cell. William Barents was a famous explorer whose ship became frozen in the ice during an attempt to get to the North Pole in 1596.

Drosophila melanogastergroucho

Mutants have more bristles in their face than normal, as does Groucho Marx.

Drosophila melanogasterscott of the antarctic

One pole of the mitotic spindle (which arranges the chromosomes during cell division) is defective in the mutant. Robert F. Scott's Antarctic expedition ended tragically in 1913.

Drosophila melanogastervan gogh

Swirling wing hair patterns in the mutants resemble van Gogh's paintings.

Drosophila melanogasteryuri

These mutants are have problems with gravity. Gene was found on the 40th anniversary of Yuri Gagarin's historic space flight.

Drosophila melanogasterglass-bottom boat

The glass-bottom boat flies' larvae are transparent.

Drosophila melanogasterindy

After the movie Monty Python and Holy Grail, in which a person taken to be buried protests: I'm not dead yet! The average life span of mutants is namely doubled.

Drosophila melanogasterken and barbie

Both male and female mutants lack external genitalia, as do poor Ken and Barbie.

Drosophila melanogasterkojak

Kojak flies lack wing bristles. Kojak (Telly Savalas), the hard-boiled cop, lacked something on his head. The gene is also known with the name shavenoid.

Drosophila melanogasterkuzbanian

In the original Muppet Show, Koozbanians were an alien lifeform known from their uncontrollable hair growth. Kuzbanian flies have uncontrollable growth of bristles in their wings. The spelling is different due to copyright reasons.

Drosophila melanogasterlost in space

Developing axons of the nerve cells are abnormally projected. (Well, the name is not THAT clever, but what about the new movie, then?)

Drosophila melanogastermaggie

Development is arrested in mutants, as seems to have happened to Maggie of Simpons.

Drosophila melanogastertribbles

Some cells in the tribbles mutants divide uncontrollably. The name is from the original Star Trek episode 'The Trouble with Tribbles'. The more the tribbles ate, the faster they multiplied.

Drosophila melanogasterdaeh

Head involution is disturbed in mutants.

Drosophila melanogaster18wheeler

The 18-wheeler gene is expressed in 18 stripes in developing larva.

Drosophila melanogasteragnostic

Agnostic flies do not learn odors in certain temperatures. Agnostic people have also
problems in making up their mind.