Clever Gene Names

Mutant males aren't interested in females. Later, more politically renamed as fruitless.

Female icebox mutants do not care about courting males.

The gene is involved in protein transport.

Mutation causes increased affection to alcohol.

The gene interacts with string.

Suzan Lewis, working in the FlyBase release 3 annotation project, writes about naming the gene: "It is the middle of the night (2:38 to be precise), I am away from friends and family, It has been this way for over 2 years, I can't sleep because of all the work there is yet to do, and there is no end in sight. So when do the magic little elves appear out of nowhere and get everything done?"

Mutant males get stuck in females.

Mutant flies' brains have swiss-cheese-like holes.

Cheryl Van Buskirk writes: "The mutant ovaries produce egg chambers that contain eight instead of sixteen cells. Since there are 16oz in a pint, we figured it was a pretty fitting name. Half pint is also an informal term for a very short person, and it so happens that the mutant eggs were indeed quite short. Sadly, the official gene name has since become Dmel/pUf68, based on its molecular weight and homology to poly-U binding splicing factors, and the name half pint is considered a synonym."

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Hip and hop gene products help other proteins to fold correctly. That is, many proteins require them to acquire the correct 3D structure. For those in doubt, Mc Hawking proves that science and hiphop belong inseparably together. (The primary official names listed by HUGO for these genes are almost equally humorous ST13 and STIP1.)

Proteins coded by mad and max bind to each other and take care that genes do not work at the wrong time. Mad Max (Mel Gibson) was on the good side, as well.

The gene was first found in fruit fly. It was named hedgehog, as the mutant larvae resembled a hedgehog. One of the human hedgehog genes was named sonic hedgehog, according to the Sega computer game character.

This is the handy official symbol of the arylsulfatase E gene.

This jolly gene (full name: tumor necrosis factor receptor subfamily, member 1B) is also known as TNFR2, TNFBR, TNFR-75 kD, TNFR-80 kD, p75TNFR, p75 and CD120b. In other words, quite normal for a human gene.

Luciferase is a common name for enzymes that catalyze reactions producing light. The name luciferase was coined by the German electrophysiologist Emil Heinrich DuBois-Reymond. Lucifer, the fallen angel, is also known as the light-giver.

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The gene guides growing nerve axons in grasshopper. Lazarillo earns his living by guiding a blind person in a 16. century Spanish novel by an anonymous author "La vida de Lazarillo de Tormes y de sus fortunas y adversidades contadas por el mismo" or  "The Life of Lazarillo of Tormes, his fortunes and misfortunes as told by himself."